
Description
Job Title: Associate Scientist
Location: Lexington, MA,
Duration: 1 year
Reporting expectations: Onsite, 5 days/wk
Top Requirements for this role:
1. Human iPSC-derived neuron culture experience
2. Gene perturbations using siRNA and/or CRISPR
3. Cell-based molecular and biochemical assays including (at least 2-3 of these 5 skillsets):
1) qPCR
2) immunocytochemistry
3) micro-electrode array (MEA)
4) fluorescence microscopy
5) ELISA
JOB DESCRIPTION:
We are seeking a highly motivated and detail-oriented scientist to join the Humanized In Vitro Model Development team. The successful candidate will contribute to the development of human iPSC-derived neuronal models and assays to support drug discovery and translational research. This is an exciting opportunity to work at the forefront of human-relevant neuroscience in a collaborative and innovative environment.
Key Responsibilities:
• Culture, differentiate, and maintain human iPSC-derived neurons.
• Perform routine cell-based and molecular assays including immunocytochemistry, qPCR, ELISA, MEA, luciferase, western blot, and fluorescence microscopy.
• Conduct functional gene perturbations and pharmacological interventions.
• Support assay development and optimization for phenotypic screening and mechanistic studies.
• Analyze and interpret experimental data, maintain accurate records, and present findings in team meetings.
• Collaborate cross-functionally with scientists in different units.
• Contribute to protocol development, SOP documentation, and continuous improvement initiatives.
Qualifications:
• Bachelor's or Master's degree in Neuroscience, Cell Biology, Stem Cell Biology, or a related field.
• LEVEL II - Minimum of 3 years professional exp w/at least 2 years of hands-on experience with human iPSC-derived neuronal cell models and assays.
• LEVEL III - Minimum of 5 years of hands-on experience with human iPSC-derived neuronal cell models and assays.
• Proficiency in cell-based assay techniques and fluorescence microscopy.
• Strong organizational and communication skills.
• Ability to work independently and collaboratively in a fast-paced research environment.
• Comfortable working with electronic lab notebooks.
Preferred Skills:
• Experience with CRISPR editing, RNA-seq, calcium imaging, high-content imaging, or complex co-culture systems is plus.
• Knowledge of automated liquid handling systems and high-throughput screening platforms.
• Familiarity with cardiometabolic diseases is a plus.
As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly® Science & Clinical?
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Work changes everything. And at Kelly, we're obsessed with where it can take you. To us, it's about more than simply accepting your next job opportunity. It's the fuel that powers every next step of your life. It's the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year.Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
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